Mingdong Dong et al 2007 Nanotechnology 18 185501 doi:10.1088/0957-4484/18/18/185501
Mingdong Dong1,2, Kenneth A Howard1,3, David Oupicky4, Harender Bisht4, Jørgen Kjems1,3 and Flemming Besenbacher1,2,5
Show affiliationsThermo-responsive nanocarriers aim to improve the delivery of drugs into target tissue by a process of size-mediated deposition activated by thermal stimuli. The direct imaging of thermally-induced changes in nanocarrier morphology was demonstrated using in situ liquid AFM over a nano-scale and temperature range relevant for clinical approaches. In situ AFM proved to be a unique method for investigating the dynamic conformational changes of individual nanoparticles, promoting its application in the future development of stimuli-responsive nanocarriers.
Issue 18 (9 May 2007)
Received 3 January 2007, in final form 23 February 2007
Published 5 April 2007
Mingdong Dong et al 2007 Nanotechnology 18 185501
Alberto Carlini et al 2008 J. Phys. A: Math. Theor. 41 045303
N A Court et al 2008 Supercond. Sci. Technol. 21 015013
S. Camelio et al 2007 EPL 79 47002
S Deser 2003 Class. Quantum Grav. 20 L213
Antonio M Puertas et al 2005 J. Phys.: Condens. Matter 17 L271
D Bazeia et al 2003 J. Phys. A: Math. Gen. 36 9943
M E Cates et al 2004 J. Phys.: Condens. Matter 16 S4861
Yiquan Wang 2006 Europhys. Lett. 74 261
Jay Gambetta and H M Wiseman 2005 J. Opt. B: Quantum Semiclass. Opt. 7 S250