Xiangyang Shi et al 2006 Nanotechnology 17 1072 doi:10.1088/0957-4484/17/4/038
Xiangyang Shi1, T Rose Ganser1, Kai Sun2, Lajos P Balogh1 and James R Baker Jr1
Show affiliationsMonodispersed, highly crystalline dendrimer-stabilized gold nanoparticles (Au DSNPs) were synthesized via hydrazine reduction chemistry and stabilized using primary amine-terminated poly(amidoamine) (PAMAM) dendrimers of different generations (generations 2–6) with the same molar ratios of dendrimer terminal nitrogen ligands/gold atoms. The sizes of the synthesized Au DSNPs decrease with the increase of the number of dendrimer generations. These Au DSNPs are fluorescent and display strong blue emission intensity at 458 nm. Polyacrylamide gel electrophoresis (PAGE) analysis indicates that all Au DSNPs are stable and both metal NPs and dendrimer stabilizers do not separate from each other during the electrophoresis process. The synthesized inorganic/organic hybrid Au DSNPs provide new nanoplatforms that will be further modified with various biological ligands for the application of biosensing and targeted cancer therapeutics.
81.07.Pr Organic-inorganic hybrid nanostructures
82.45.Yz Nanostructured materials in electrochemistry
78.67.Bf Nanocrystals and nanoparticles
68.70.+w Whiskers and dendrites (growth, structure, and nonelectronic properties)
Surfaces, interfaces and thin films
Issue 4 (28 February 2006)
Received 12 October 2005, in final form 13 December 2005
Published 30 January 2006
Xiangyang Shi et al 2006 Nanotechnology 17 1072