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Quantitative force measurements using frequency modulation atomic force microscopy—theoretical foundations

John E Sader1,4, Takayuki Uchihashi2, Michael J Higgins2, Alan Farrell2, Yoshikazu Nakayama3 and Suzanne P Jarvis2

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Use of the atomic force microscope (AFM) in quantitative force measurements inherently requires a theoretical framework enabling conversion of the observed deflection properties of the cantilever to an interaction force. In this paper, the theoretical foundations of using frequency modulation atomic force microscopy (FM-AFM) in quantitative force measurements are examined and rigorously elucidated, with consideration being given to both 'conservative' and 'dissipative' interactions. This includes a detailed discussion of the underlying assumptions involved in such quantitative force measurements, the presentation of globally valid explicit formulae for evaluation of so-called 'conservative' and 'dissipative' forces, discussion of the origin of these forces, and analysis of the applicability of FM-AFM to quantitative force measurements in liquid.


PACS

68.37.Ps Atomic force microscopy (AFM)

62.25.-g Mechanical properties of nanoscale systems

Subjects

Surfaces, interfaces and thin films

Nanoscale science and low-D systems

Dates

Issue 3 (March 2005)

Received 22 November 2004, in final form 12 December 2004

Published 25 January 2005



  1. Quantitative force measurements using frequency modulation atomic force microscopy—theoretical foundations

    John E Sader et al 2005 Nanotechnology 16 S94

  2. Comparison of pressure standards in the range 10 kPa to 140 kPa

    M Perkin et al 1999 Metrologia 36 160

  3. Filling in dentinal tubules

    Ming-Han Liu et al 2007 Nanotechnology 18 475104

  4. Phase separation in confined systems

    Lev D Gelb et al 1999 Rep. Prog. Phys. 62 1573

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