Wolfgang J Parak 1,3, Teresa Pellegrino 1 and Christian Plank 2
1
Center for Nanoscience, Ludwig Maximilians Universität München, Amalienstrasse 54, 80799 München, Germany
2
Institute of Experimental Oncology, Technische Universität München, Ismaninger Strasse 22, 81675 München, Germany
3
Author to whom any correspondence should be addressed
Wolfgang J Parak et al 2005 Nanotechnology 16 R9
Colloidal quantum dots are semiconductor nanocrystals well dispersed in a solvent. The optical properties of quantum dots, in particular the wavelength of their fluorescence, depend strongly on their size. Because of their reduced tendency to photobleach, colloidal quantum dots are interesting fluorescence probes for all types of labelling studies. In this review we will give an overview on how quantum dots have been used so far in cell biology. In particular we will discuss the biologically relevant properties of quantum dots and focus on four topics: labelling of cellular structures and receptors with quantum dots, incorporation of quantum dots by living cells, tracking the path and the fate of individual cells using quantum dot labels, and quantum dots as contrast agents.
87.64.-t Spectroscopic and microscopic techniques in biophysics and medical physics
Issue 2 (February 2005)
Received 2 September 2004
,
in final form 15 December 2004
Published 25 January 2005
Wolfgang J Parak et al 2005 Nanotechnology 16 R9
Anatoliy Pinchuk 2003 J. Phys. D: Appl. Phys. 36 460
J E Dyson 1976 Phys. Educ. 11 100
fullerite hydrogenated under high pressure; evidence for interstitial molecular hydrogen
A I Kolesnikov et al 1997 J. Phys.: Condens. Matter 9 2831
W Culshaw 1953 Proc. Phys. Soc. B 66 597
Mark Foskey et al 2005 Phys. Med. Biol. 50 5869
B. A. Whitney et al 2008 The Astronomical Journal 136 18
D del-Castillo-Negrete et al 2004 Plasma Phys. Control. Fusion 46 A105
Oskar Painter et al 2001 J. Opt. A: Pure Appl. Opt. 3 S161