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Design and implementation of a cost-effective microscope for fabrication and imaging

G Trout and S Basu

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TECHNICAL DESIGN NOTE

The use of lasers and optical systems for advanced research and demonstrative purposes has traditionally been cost-prohibitive for many researchers. In this note, we present the design and optimization of a low-cost microscopy setup capable of imaging, fabrication or photopolymerization via multiphoton excitation of a photoactivator and the study of processes such as diffusion using fluorescence recovery after photobleaching (FRAP). The setup features a continuous wave (CW) Ar-ion laser, a pulsed Nd3+:YAG laser, an inverted microscope with a CCD camera and appropriate optics. The setup is cost-effective and puts a once-expensive setup within reach of more researchers interested in micron- and sub-micron-scale processes.


PACS

07.60.Pb Conventional optical microscopes

82.35.-x Polymers: properties; reactions; polymerization

42.50.Gy Effects of atomic coherence on propagation, absorption, and amplification of light; electromagnetically induced transparency and absorption

Subjects

Soft matter, liquids and polymers

Instrumentation and measurement

Optics, quantum optics and lasers

Chemical physics and physical chemistry

Dates

Issue 12 (December 2009)

Received 4 August 2009

Published 29 October 2009



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