Florian Bender et al 2009 Meas. Sci. Technol. 20 124011 doi:10.1088/0957-0233/20/12/124011
Florian Bender1, Paul Roach2, Achilleas Tsortos1, George Papadakis1,3, Michael I Newton2, Glen McHale2 and Electra Gizeli1,3
Show affiliationsIt is known that acoustic sensor devices, if operated in liquid phase, are sensitive not just to the mass of the analyte but also to various other parameters, such as size, shape, charge and elastic constants of the analyte as well as bound and viscously entrained water. This can be used to extract valuable information about a biomolecule, particularly if the acoustic device is combined with another sensor element which is sensitive to the mass or amount of analyte only. The latter is true in good approximation for various optical sensor techniques. This work reports on the development of a combined surface plasmon resonance/surface acoustic wave sensor system which is designed for the investigation of biomolecules such as proteins or DNA. Results for the deposition of neutravidin and DNA are reported.
87.80.-y Biophysical techniques (research methods)
87.15.M- Spectra of biomolecules
Issue 12 (December 2009)
Received 28 May 2009, in final form 13 July 2009
Published 26 October 2009
Florian Bender et al 2009 Meas. Sci. Technol. 20 124011
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E N Landis and J E Bolander 2009 J. Phys. D: Appl. Phys. 42 214002
H B Cao et al 2009 J. Phys.: Condens. Matter 21 492202
S Q Liang et al 2009 J. Phys.: Conf. Ser. 188 012022
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