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Combinatorial and high-throughput approaches in polymer science

Huiqi Zhang, Richard Hoogenboom, Michael A R Meier and Ulrich S Schubert

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Combinatorial and high-throughput approaches have become topics of great interest in the last decade due to their potential ability to significantly increase research productivity. Recent years have witnessed a rapid extension of these approaches in many areas of the discovery of new materials including pharmaceuticals, inorganic materials, catalysts and polymers. This paper mainly highlights our progress in polymer research by using an automated parallel synthesizer, microwave synthesizer and ink-jet printer. The equipment and methodologies in our experiments, the high-throughput experimentation of different polymerizations (such as atom transfer radical polymerization, cationic ring-opening polymerization and emulsion polymerization) and the automated matrix-assisted laser desorption/ionization time-of-flight mass spectroscopy (MALDI-TOF MS) sample preparation are described.


PACS

82.35.-x Polymers: properties; reactions; polymerization

Subjects

Soft matter, liquids and polymers

Chemical physics and physical chemistry

Dates

Issue 1 (January 2005)

Received 30 April 2004

Published 16 December 2004



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