Giuseppe Zaccai 2003 J. Phys.: Condens. Matter 15 S1673 doi:10.1088/0953-8984/15/18/301
Giuseppe Zaccai1
Show affiliationsA protein is a nano-machine whose molecular structure was selected by evolution to perform specific biological functions. Neutron spectroscopy is uniquely suited to provide experimental data on atomic motions in a protein under the influence of forces that maintain its stable and active molecular structure. Experiments are reviewed relating such a dynamics to soluble protein folding and stability in different environments, and to the activity of bacteriorhodopsin, a membrane protein nano-machine with light-driven proton pump activity.
87.15.B- Structure of biomolecules
87.80.-y Biophysical techniques (research methods)
87.15.H- Dynamics of biomolecules
87.15.Cc Folding: thermodynamics, statistical mechanics, models, and pathways
Issue 18 (14 May 2003)
Received 16 October 2002
Published 28 April 2003
Giuseppe Zaccai 2003 J. Phys.: Condens. Matter 15 S1673
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