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Coexisting liquid phases in lipid monolayers and bilayers

Sarah L Keller

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Several mixtures of phospholipids and cholesterol produce coexisting liquid phases when deposited as a monolayer at an air-water interface. For model mixtures near the miscibility critical point, distinctive `stripe' phases are observed. Stripe phases are also observed in monolayers with lipid compositions approximating the inner or outer leaflets of human red blood cells. For monolayers containing cholesterol and lipids with high melting temperature, the phase diagram can exhibit two upper miscibility critical points rather than only one.


PACS

87.14.Cc Lipids

68.03.Cd Surface tension and related phenomena

87.16.D- Membranes, bilayers, and vesicles

87.15.N- Properties of solutions of macromolecules

Subjects

Soft matter, liquids and polymers

Surfaces, interfaces and thin films

Biological physics

Dates

Issue 19 (20 May 2002)

Received 21 November 2001

Published 2 May 2002



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