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Application of XFEL to the measurement of x-ray flux irradiating bio-molecules by using x-ray emission from hollow atoms produced from multiple x-ray absorption

Kengo Moribayashi

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We propose the measurement of x-ray flux irradiating bio-molecules by the theoretical treatment of atomic processes together with multiple x-ray absorption. This measurement is useful for the application of x-ray free electron lasers to the measurement of diffraction patterns of bio-molecules, which is indispensable for the study of their three-dimensional structure. The charge numbers of atoms such as C, N, O in bio-molecules, which appear in the fluorescent x-ray spectroscopy from singly inner-shell ionized atoms and hollow atoms, may inform us of the x-ray flux. Furthermore, it is found that the ratio of the number of fluorescent x-ray photons from the hollow atoms to that from the singly inner-shell ionized atoms is in proportion to the x-ray flux irradiating these atoms. This ratio may also be used for the measurement of the x-ray flux.


PACS

87.53.-j Effects of ionizing radiation on biological systems

87.15.M- Spectra of biomolecules

87.15.B- Structure of biomolecules

87.14.E- Proteins

Subjects

Biological physics

Medical physics

Dates

Issue 8 (28 April 2008)

Received 14 November 2007, in final form 10 March 2008

Published 8 April 2008



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