D. Houtman et al 2007 EPL 78 18001 doi:10.1209/0295-5075/78/18001
D. Houtman1, I. Pagonabarraga2, C. P. Lowe1, A. Esseling-Ozdoba3, A. M. C. Emons3 and E. Eiser1
Show affiliationsWe develop a simple lattice model to describe the hydrodynamic influence of active mass transport along bio-filaments on freely diffusing mass in the cell. To quantify the overall mass transport we include Brownian motion, excluded volume interactions, active transport along the filaments, and hydrodynamic interactions. The model shows that the hydrodynamic forces induced by molecular motors attached to the filaments give rise to a non-negligible flux close to the filament. This additional flux appears to have two effects. Depending on the degree of filament occupation it can exert a sufficiently large influence on unbound motors and cargo to modify their transport and also regulate the flux of motors bound to the filament. We expect such a mechanism is important in situations found in plant cells, where directional transport spans the entire cell. In particular, it can explain the cytoplasmic streaming observed in plant cells.
67.25.dg Transport, hydrodynamics, and superflow
87.16.Nn Motor proteins (myosin, kinesin dynein)
05.40.-a Fluctuation phenomena, random processes, noise, and Brownian motion
Issue 1 (April 2007)
Received 9 July 2006, in final form 12 February 2007
Published 14 March 2007
D. Houtman et al 2007 EPL 78 18001
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J. C. Pandey et al. 2005 The Astronomical Journal 130 1231
Richard A. Carrigan Jr 2009 ApJ 698 2075
Jan-Uwe Ness et al. 2003 ApJ 598 1277