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Environmental Impacts on Spiking Properties in Hodgkin–Huxley Neuron with Direct Current Stimulus

Yuan Chang-Qing, Zhao Tong-Jun, Zhan Yong, Zhang Su-Hua, Liu Hui and Zhang Yu-Hong

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CROSS-DISCIPLINARY PHYSICS AND RELATED AREAS OF SCIENCE AND TECHNOLOGY

Based on the well accepted Hodgkin–Huxley neuron model, the neuronal intrinsic excitability is studied when the neuron is subject to varying environmental temperatures, the typical impact for its regulating ways. With computer simulation, it is found that altering environmental temperature can improve or inhibit the neuronal intrinsic excitability so as to influence the neuronal spiking properties. The impacts from environmental factors can be understood that the neuronal spiking threshold is essentially influenced by the fluctuations in the environment. With the environmental temperature varying, burst spiking is realized for the neuronal membrane voltage because of the environment-dependent spiking threshold. This burst induced by changes in spiking threshold is different from that excited by input currents or other stimulus.


PACS

87.18.Sn Neural networks and synaptic communication

87.17.Aa Modeling, computer simulation of cell processes

87.19.L- Neuroscience

Subjects

Medical physics

Biological physics

Dates

Issue 11 (November 2009)

Received 5 August 2009



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