Ugo Amaldi and Gerhard Kraft 2005 Rep. Prog. Phys. 68 1861 doi:10.1088/0034-4885/68/8/R04
Ugo Amaldi1 and Gerhard Kraft2
Show affiliationsIn cancer treatment, the introduction of MeV bremsstrahlung photons has been instrumental in delivering higher doses to deep-seated tumours, while reducing the doses absorbed by the surrounding healthy tissues. Beams of protons and carbon ions have a much more favourable dose-depth distribution than photons (called 'x-rays' by medical doctors) and are the new frontiers of cancer radiation therapy. Section 2 presents the status of the first form of hadrontherapy which uses beams of 200–250 MeV protons. The central part of this review is devoted to the discussion of the physical, radiobiological and clinical bases of the use of 400 MeV µ−1 carbon ions in the treatment of radio-resistant tumours. These resist irradiation with photon as well as proton beams. The following section describes the carbon ion facilities that are either running or under construction. Finally, the projects recently approved or proposed are reviewed here.
Issue 8 (August 2005)
Received 23 February 2005, in final form 1 June 2005
Published 11 July 2005
Ugo Amaldi and Gerhard Kraft 2005 Rep. Prog. Phys. 68 1861
S Y Tong and Huasheng Wu 2002 J. Phys.: Condens. Matter 14 1231
Yuan H Guan et al 2004 Smart Mater. Struct. 13 1230
Thomas S Duffy 2005 Rep. Prog. Phys. 68 1811
S Velasco et al 1993 Eur. J. Phys. 14 166
E Pickwell et al 2004 Phys. Med. Biol. 49 1595
M R Koblischka et al 1997 Supercond. Sci. Technol. 10 693
Guy Ratel 2007 Metrologia 44 S102
Li Bin et al 2001 Chinese Phys. Lett. 18 181
Ruby Gupta et al 2004 J. Phys. D: Appl. Phys. 37 1091