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Magnetoencephalography - a noninvasive brain imaging method with 1 ms time resolution

REVIEW ARTICLE

Cosimo Del Gratta1,2,3, Vittorio Pizzella1,2,3, Franca Tecchio4 and Gian Luca Romani1,2,3

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The basics of magnetoencephalography (MEG), i.e. the measurement and the analysis of the tiny magnetic fields generated outside the scalp by the working human brain, are reviewed. Three main topics are discussed: (1) the relationship between the magnetic field and its generators, including on one hand the neurophysiological basis and the physical theory of magnetic field generation, and on the other hand the techniques for the estimation of the sources from the magnetic field measurements; (2) the instrumental techniques and the laboratory practice of neuromagnetic field measurement and (3) the main applications of MEG in basic neurophysiology as well as in clinical neurology.


PACS

87.80.-y Biophysical techniques (research methods)

87.50.C- Static and low-frequency electric and magnetic fields effects

87.19.L- Neuroscience

Subjects

Instrumentation and measurement

Medical physics

Biological physics

Dates

Issue 12 (December 2001)

Received 26 June 2001, in final form 6 September 2001

Published 15 November 2001



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