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Ultrasound-based transient elastography compared to magnetic resonance elastography in soft tissue-mimicking gels

Jennifer Oudry1,2,4, Jonathan Vappou1,4,5, Philippe Choquet3, Rémy Willinger1, Laurent Sandrin2 and André Constantinesco3

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Ultrasound-based transient elastography (TE) and magnetic resonance elastography (MRE) are increasingly used methods for the clinical evaluation of soft tissue mechanical properties and their alteration under diseased conditions. This study proposes a comparison between magnetic resonance elastography (MRE) and ultrasound-based transient elastography (TE). Both methods were tested on the same soft tissue-mimicking gels in a common frequency range in order to allow for direct quantitative comparison. For the four gels tested, relatively good agreement was found between the shear moduli measured by both methods, with an averaged relative difference of 23%. This study demonstrates that under the assumption of homogeneous media that are significantly more elastic than viscous, quantitative results obtained by both methods are comparable.


PACS

87.63.D- Ultrasonography

87.19.R- Mechanical and electrical properties of tissues and organs

87.19.X- Diseases

87.61.Tg Clinical applications

Subjects

Biological physics

Medical physics

Dates

Issue 22 (21 November 2009)

Received 22 December 2008, in final form 7 October 2009

Published 4 November 2009



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