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Photoacoustic tomography and sensing in biomedicine

FEATURED ARTICLE REVIEW ARTICLE

Changhui Li and Lihong V Wang

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TOPICAL REVIEW

Photoacoustics has been broadly studied in biomedicine, for both human and small animal tissues. Photoacoustics uniquely combines the absorption contrast of light or radio frequency waves with ultrasound resolution. Moreover, it is non-ionizing and non-invasive, and is the fastest growing new biomedical method, with clinical applications on the way. This review provides a brief recap of recent developments in photoacoustics in biomedicine, from basic principles to applications. The emphasized areas include the new imaging modalities, hybrid detection methods, photoacoustic contrast agents and the photoacoustic Doppler effect, as well as translational research topics.


PACS

87.63.L- Visual imaging

43.35.Ud Thermoacoustics, high temperature acoustics, photoacoustic effect

42.30.Wb Image reconstruction; tomography

42.62.Be Biological and medical applications

87.63.D- Ultrasonography

Subjects

Biological physics

Optics, quantum optics and lasers

Medical physics

Dates

Issue 19 (7 October 2009)

Received 3 February 2009, in final form 4 August 2009

Published 1 September 2009



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