Quick search Find article
Quick search
Find article

Development of a remanence measurement-based SQUID system with in-depth resolution for nanoparticle imaging

Song Ge1,2, Xiangyang Shi2,4, James R Baker Jr2, Mark M Banaszak Holl2,3 and Bradford G Orr1,2,4

Show affiliations


NOTE

We present a remanence measurement method using a superconducting quantum interference device (SQUID) to detect trace amounts of magnetic nanoparticles (MNPs). Based on this method, a one-dimensional scanning system was established for imaging. The system was calibrated with 25 nm diameter Fe2O3 nanoparticles (NPs), and the sensitivity of the NPs was found to be 10 ng at a distance of 1.7 cm and the spatial resolution was ~1 cm. A theoretical model of this system was developed and applied to the deconvolution of scanned images of phantoms with two NP injection spots. Using the developed SQUID system, we were able to determine not only the amount and horizontal positions of the injections, but also their depths in the phantoms.


PACS

87.85.Qr Nanotechnologies-design

87.57.C- Image quality

07.55.Ge Magnetometers for magnetic field measurements

87.56.Da Ancillary equipment

85.25.Dq Superconducting quantum interference devices (SQUIDs)

Subjects

Superconductivity

Instrumentation and measurement

Medical physics

Dates

Issue 10 (21 May 2009)

Received 9 February 2009, in final form 20 March 2009

Published 27 April 2009



  1. Development of a remanence measurement-based SQUID system with in-depth resolution for nanoparticle imaging

    Song Ge et al 2009 Phys. Med. Biol. 54 N177

  2. Renormalization of the phase transition in lead phosphate, Pb3(PO4)2, by high pressure: structure

    R J Angel et al 2001 J. Phys.: Condens. Matter 13 5353

  3. HD 147506b: A Supermassive Planet in an Eccentric Orbit Transiting a Bright Star

    G. Á. Bakos et al. 2007 ApJ 670 826

  4. Frictional quantum decoherence

    Bruno Bellomo et al 2007 J. Phys. A: Math. Theor. 40 9437

  5. On the concepts of Lie and covariant derivatives of spinors: part II

    D J Hurley and M A Vandyck 1994 J. Phys. A: Math. Gen. 27 5941

  6. Avalanche processes in an idealized lamp: I. Measurements of formative breakdown time

    Richard S Moss et al 2004 J. Phys. D: Appl. Phys. 37 2502

  7. Boundary charges in gauge theories: using Stokes theorem in the bulk

    Glenn Barnich 2003 Class. Quantum Grav. 20 3685

  8. The commutativity of quantized first- and higher-order Hamiltonians

    K Ikeda 1994 J. Phys. A: Math. Gen. 27 5969

  9. The 'unromantic pictures' of quantum theory

    Roderich Tumulka 2007 J. Phys. A: Math. Theor. 40 3245

  10. Normal frames for non-Riemannian connections

    David Hartley 1995 Class. Quantum Grav. 12 L103

View by subject




Export








Please login to access our web services, or create an account if you don't yet have one.

You must have cookies enabled in your web browser to be able to login.

Username
Password

Forgotten your password? Get a new one here.