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Evaluation of x-ray diffraction enhanced imaging in the diagnosis of breast cancer

Chenglin Liu1,2, Xiaohui Yan1, Xinyi Zhang1,3, Wentao Yang4, Weijun Peng4, Daren Shi4, Peiping Zhu5, Wanxia Huang5 and Qingxi Yuan5

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The significance of the x-ray diffraction enhanced imaging (DEI) technique in the diagnosis of breast cancer and its feasibility in clinical medical imaging are evaluated. Different massive specimens including normal breast tissues, benign breast tumour tissues and malignant breast tumour tissues are imaged with the DEI method. The images are recorded respectively by CCD or x-ray film at different positions of the rocking curve and processed with a pixel-by-pixel algorithm. The characteristics of the DEI images about the normal and diseased tissues are compared. The rocking curves of a double-crystal diffractometer with various tissues are also studied. The differences in DEI images and their rocking curves are evaluated for early diagnosis of breast cancers.


PACS

87.59.-e X-ray imaging

87.19.X- Diseases

87.64.Bx Electron, neutron and x-ray diffraction and scattering

87.63.-d Non-ionizing radiation equipment and techniques

Subjects

Biological physics

Medical physics

Dates

Issue 2 (21 January 2007)

Received 8 March 2006, in final form 20 August 2006

Published 29 December 2006



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