J J Luci et al 2007 Phys. Med. Biol. 52 N241 doi:10.1088/0031-9155/52/10/N03
J J Luci1,2, H M Whitney1,3 and J C Gore1,2,3
Show affiliationsPolymer gel dosimetry aims to provide three-dimensional images of radiation therapy dose distributions in irradiated aqueous gels. The first gels required manufacture in an oxygen-free environment, but later the MAGIC formulation was introduced, which could be made in normal atmospheric conditions. Here we report our studies of the effects of variations in the composition of the MAGIC gel performed in order to optimize its performance over the useful dose range of 0 to 20 Gy. A new formulation (termed 'MAGIC-2') is comprised of 87% water, 4% methacrylic acid, 9% gelatin, 17.38 × 10−6 M Cu2+ and a molar ratio of ascorbic acid to [Cu2+] of 1000:1. MAGIC-2 has a dose–response slope-to-intercept ratio that is 78% greater than the original formulation and other more favorable properties.
Issue 10 (21 May 2007)
Received 14 September 2006, in final form 28 March 2007
Published 24 April 2007
J J Luci et al 2007 Phys. Med. Biol. 52 N241
V I Donin et al 2003 J. Phys. D: Appl. Phys. 36 2366
I A Ivanov and A S Kheifets 2005 J. Phys. B: At. Mol. Opt. Phys. 38 2245
Martin Lepage et al 2007 Phys. Med. Biol. 52 N249
Jun Cui et al. 2005 ApJ 633 649
Franz Wegner 2006 J. Phys. A: Math. Gen. 39 8221
Taekyun Kim et al 2001 J. Phys. A: Math. Gen. 34 7633
K. Ishibashi et al. 1999 ApJ 524 983
R A Lippert et al 2006 J. Phys.: Condens. Matter 18 4295
Y Abou-Ali et al 2004 J. Phys. B: At. Mol. Opt. Phys. 37 2855