Hua Deng et al 2007 Phys. Med. Biol. 52 2729 doi:10.1088/0031-9155/52/10/007
Hua Deng1, Christopher W Kennedy1, Elwood Armour1, Erik Tryggestad1, Eric Ford1, Todd McNutt1, Licai Jiang2 and John Wong1
Show affiliationsA small animal radiation platform equipped with on-board cone-beam CT and conformal irradiation capabilities is being constructed for translational research. To achieve highly localized dose delivery, an x-ray lens is used to focus the broad beam from a 225 kVp x-ray tube down to a beam with a full width half maximum (FWHM) of approximately 1.5 mm in the energy range 40–80 keV. Here, we report on the dosimetric characteristics of the focused beam from the x-ray lens subsystem for high-resolution dose delivery. Using the metric of the average dose within a 1.5 mm diameter area, the dose rates at a source-to-surface distance (SSD) of 34 cm are 259 and 172 cGy min−1 at 6 mm and 2 cm depths, respectively, with an estimated uncertainty of ±5%. The per cent depth dose is approximately 56% at 2 cm depth for a beam at 34 cm SSD.
87.53.Kn Conformal radiation treatment
Issue 10 (21 May 2007)
Received 30 January 2007, in final form 22 February 2007
Published 26 April 2007
Hua Deng et al 2007 Phys. Med. Biol. 52 2729
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