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Nuclear medicine dosimetry

REVIEW ARTICLE

Michael Stabin

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REVIEW

A brief overview is provided of the history of the development of internal dose methods for use in nuclear medicine. Basic methods of internal dosimetry and the systems that have been developed for use in nuclear medicine are described. The development of the MIRD system and the International Radiopharmaceutical Dosimetry Symposium series is outlined. The evolution of models and tools for calculating dose estimates is reviewed. Current efforts in developing more patient-specific methods, particularly for use in therapy calculations, development of small scale and microdosimetry techniques, and of relating internal radiation doses to observed biological effects are described and evaluated.


PACS

87.57.uq Dosimetry

87.53.-j Effects of ionizing radiation on biological systems

87.56.Da Ancillary equipment

87.57.un Radiopharmaceuticals

87.55.N- Radiation monitoring, control, and safety

Subjects

Medical physics

Dates

Issue 13 (7 July 2006)

Received 7 February 2006, in final form 7 March 2006

Published 20 June 2006



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