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Magnetic resonance spectroscopy (MRS) in the investigation of cancer at The Royal Marsden Hospital and The Institute of Cancer Research

REVIEW ARTICLE

M O Leach

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REVIEW

Developments in magnetic resonance spectroscopy (MRS) at The Royal Marsden Hospital and The Institute of Cancer Research are reviewed in the context of preceding developments in nuclear magnetic resonance (NMR) and MRS, and some of the early developments in this field, particularly those leading to human measurements. The early development of technology, and associated techniques for human measurement and assessment will be discussed, with particular reference to experience at out institutions. Applications using particular nuclei will then be described and related to other experimental work where appropriate. Contributions to the development of MRS that have been published in Physics in Medicine and Biology will be discussed.


PACS

87.64.K- Spectroscopy

87.61.Tg Clinical applications

87.19.X- Diseases

82.80.-d Chemical analysis and related physical methods of analysis

Subjects

Medical physics

Biological physics

Chemical physics and physical chemistry

Dates

Issue 13 (7 July 2006)

Received 16 March 2006, in final form 23 May 2006

Published 20 June 2006



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