A Olivo and R Speller 2006 Phys. Med. Biol. 51 3015 doi:10.1088/0031-9155/51/12/001
A Olivo and R Speller
Show affiliationsPhase contrast (PC) imaging is one of the most exciting emerging x-ray imaging techniques, with the potential of removing some of the main limitations of conventional radiology. After extensive experimentation carried out particularly at synchrotron radiation (SR) facilities, the scientific community agrees that it is now time to translate these ideas towards the first clinical implementations. In this framework, a complete model, based on Fresnel/Kirchoff diffraction integrals, was devised. This model accounts for source dimensions, beam spectrum and divergence and detector point spread function (PSF), and can thus be applied to any x-ray imaging system. In particular, by accepting in input the above parameters along with the ones describing the sample, the model can be used to optimize the geometry of the set-up, i.e. to assess the source-to-sample and sample-to-detector distances which maximize feature detection. The model was evaluated by acquiring a range of images of different samples with a laboratory source, and a good agreement was found between simulated and experimental data in all cases. In order to maximize the generality of the results, all acquisitions were carried out using a polychromatic source and an energy-resolving detector; in this way, a range of monochromatic images could be obtained as well as polychromatic images, which can be created by integrating different parts of the acquired spectra. One of the most notable results obtained is that in many practical cases polychromatic PC imaging can provide the same image quality as its monochromatic counterpart. This is an important step in the wider application of PC using conventional sources.
Issue 12 (21 June 2006)
Received 8 March 2006, in final form 10 April 2006
Published 31 May 2006
A Olivo and R Speller 2006 Phys. Med. Biol. 51 3015
S D Bartlett et al 2002 J. Phys. A: Math. Gen. 35 5599
C Lewiner and G Bastard 1978 J. Phys. C: Solid State Phys. 11 4727
David Sudarsky et al. 2005 ApJ 627 520
A Bianconi et al 2000 J. Phys.: Condens. Matter 12 10655
J. E. Krick et al. 2009 ApJ 700 123
R L Becker and A D MacKellar 1984 J. Phys. B: At. Mol. Phys. 17 3923
P Love 1983 J. Phys. C: Solid State Phys. 16 5985
Kurusch Ebrahimi-Fard et al 2004 J. Phys. A: Math. Gen. 37 11037
Achim Kempf and Paulo J S G Ferreira 2004 J. Phys. A: Math. Gen. 37 12067