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Recent advances in diffuse optical imaging

REVIEW ARTICLE

A P Gibson1, J C Hebden1 and S R Arridge2

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TOPICAL REVIEW

We review the current state-of-the-art of diffuse optical imaging, which is an emerging technique for functional imaging of biological tissue. It involves generating images using measurements of visible or near-infrared light scattered across large (greater than several centimetres) thicknesses of tissue. We discuss recent advances in experimental methods and instrumentation, and examine new theoretical techniques applied to modelling and image reconstruction. We review recent work on in vivo applications including imaging the breast and brain, and examine future challenges.


PACS

87.63.L- Visual imaging

87.19.L- Neuroscience

87.57.N- Image analysis

87.64.Cc Scattering of visible, uv, and infrared radiation

42.30.Wb Image reconstruction; tomography

Subjects

Optics, quantum optics and lasers

Biological physics

Medical physics

Dates

Issue 4 (21 February 2005)

Received 21 September 2004

Published 2 February 2005



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