Kuen-Cheng Ju et al 2003 Phys. Med. Biol. 48 167 doi:10.1088/0031-9155/48/2/303
Kuen-Cheng Ju1, Yung-Yaw Chen1, Win-Li Lin2 and Te-Son Kuo1
Show affiliationsThis paper investigates the feasibility of conformal heating for external ultrasound hyperthermia by using a phased array transducer with mechanical motion. In this system, a one-dimensional phased array is arranged on a shaft and moves along the shaft, while dynamically focusing on the planning target volume (PTV) with numerous focal spots. To prevent overheating in the intervening tissue between the skin and the PTV, the shaft and the phased array are rotated together to enlarge the acoustical window. With the purpose of conformal heating, the power deposition of the PTV is constructed by combinations of the focal spots and an iterative gradient descent method is then used to determine an optimal set of power weightings for the focal spots. Different tumour shapes are evaluated and the simulation results demonstrate that the volume percentage of the PTV with temperatures higher than 43 °C is over 95%. The overheating volume outside the PTV is less than 25% of the PTV. This method provides good conformal heating for external ultrasound hyperthermia. The concept of combining electrical focusing and mechanical motion has the advantages of both enlarging the acoustic window and providing dynamic focusing ability, which is essential for successful conformal heating.
87.50.wp Therapeutic applications
Issue 2 (21 January 2003)
Received 6 June 2002, in final form 18 November 2002
Published 23 December 2002
Kuen-Cheng Ju et al 2003 Phys. Med. Biol. 48 167
Z Jiang 2008 Metrologia 45 S6
R Felder 2005 Metrologia 42 323
Chris King and Peter Kennett 2002 Phys. Educ. 37 467
R S Davis 1992 Metrologia 29 67
Wolfgang J Parak et al 2005 Nanotechnology 16 R9
Wang Jian-Bo et al 2004 Chinese Phys. Lett. 21 945
Rajesh Das and Swati Ray 2003 J. Phys. D: Appl. Phys. 36 152
T Dray and G 't Hooft 1986 Class. Quantum Grav. 3 825
M E Gouvea et al 1990 J. Phys.: Condens. Matter 2 1853