S Mair et al 2002 Phys. Med. Biol. 47 3719 doi:10.1088/0031-9155/47/21/307
S Mair, B Gompf and M Dressel
Show affiliationsA novel THz near-field spectrometer is presented which allows the performance of biological and medical studies with high spectral resolution combined with a spatial resolution down to λ/100. In the setup an aperture much smaller than the used wavelength is placed in the beam very close to the sample. The sample is probed by the evanescent wave behind the aperture. The distance is measured extremely accurately by a confocal microscope. We use monochromatic sources which provide powerful coherent cw radiation tuneable from 50 GHz up to 1.5 THz. Transmission and reflection experiments can be performed which enable us to study solids and molecules in aqueous solution. Examples for spectroscopic investigations on biological tissues are presented.
87.63.-d Non-ionizing radiation equipment and techniques
07.57.Hm Infrared, submillimeter wave, microwave, and radiowave sources
Issue 21 (7 November 2002)
Received 31 January 2002
Published 17 October 2002
S Mair et al 2002 Phys. Med. Biol. 47 3719
C D McGuinness et al 2004 Meas. Sci. Technol. 15 L19
J M Nester 1988 J. Phys. A: Math. Gen. 21 L1013
Ignasi Ribas et al. 2005 ApJ 622 680
L Ventura et al 2006 Phys. Med. Biol. 51 3085
A. S. Evans et al. 2002 ApJ 580 749
Yukiyasu Ozeki 1996 J. Phys. A: Math. Gen. 29 5805
T. R. Hunter et al. 2006 ApJ 649 888
D Wilkinson and J F Willemsen 1983 J. Phys. A: Math. Gen. 16 3365
A Olivo and R Speller 2006 Phys. Med. Biol. 51 3015