Quick search Find article
Quick search
Find article

Magnetocardiographic analysis of the two-dimensional distribution of intra-QRS fractionated activation

H-P Müller-+, P Gödde-+, K Czerski-+, M Oeff-+, R Agrawal-+, P Endt§, W Kruse§, U Steinhoff§ and L Trahms§

Show affiliations


The spatial distribution of high-frequency components in magnetic signals during the QRS complex of the human heartbeat was investigated. Cardiomagnetic signals were recorded simultaneously using 49 first-order magnetogradiometer channels of a multi-SQUID system with a low noise power density. The QRS fragmentation score S, as a measure of the fragmentation of the bandpass-filtered QRS complex, was examined for its sensitivity and specificity to discriminate 34 healthy volunteers, 42 post-myocardial infarction patients and 43 patients with coronary heart disease and with a history of malignant sustained ventricular tachycardia or ventricular fibrillation. The multichannel information was visualized by two-dimensional mapping of the score values of the single channels. By averaging the score values for the seven central channels, , the score values of all 49 channels, , and calculating the standard deviation for all 49 channels, , a higher sensitivity and specificity for detecting patients with ventricular tachycardia (VT) or ventricular fibrillation (VF) was reached than by analysis of a single channel. Combination of these parameters furnishes a sensitivity of 90% and a specificity of 70% for identifying patients prone to VT/VF.

The results were compared with diagnostic information obtained from the QRS duration of the signal as well as with results obtained by modified QRS integral mapping.


PACS

87.19.Hh Cardiac dynamics

87.19.Ff Muscles

85.25.Dq Superconducting quantum interference devices (SQUIDs)

87.50.C- Static and low-frequency electric and magnetic fields effects

87.19.X- Diseases

Subjects

Superconductivity

Medical physics

Biological physics

Dates

Issue 1 (January 1999)

Received 27 January 1998, in final form 28 October 1998



  1. Magnetocardiographic analysis of the two-dimensional distribution of intra-QRS fractionated activation

    H-P Müller et al 1999 Phys. Med. Biol. 44 105

  2. Volume recombination parameter in ionization chambers

    M Boutillon 1998 Phys. Med. Biol. 43 2061

  3. Ionometric determination of absorbed dose to water for cobalt-60 gamma rays

    M Boutillon and A -M Perroche 1993 Phys. Med. Biol. 38 439

  4. A comparison of absorbed dose standards for high-energy X-rays

    K R Shortt et al 1993 Phys. Med. Biol. 38 1937

  5. A fully 3D small PET scanner

    S Tavernier et al 1992 Phys. Med. Biol. 37 635

  6. Towards an ideal blood analogue for Doppler ultrasound phantoms

    C P Oates 1991 Phys. Med. Biol. 36 1433

  7. Re-evaluation of the W value for electrons in dry air

    M Boutillon and A M Perroche-Roux 1987 Phys. Med. Biol. 32 213

  8. A Coincident Gamma-Ray Spectrometer and its application to measurements of Low Level Radioactivity

    T R Overton and P R J Burch 1966 Phys. Med. Biol. 11 47

  9. Leidenfrost point and estimate of the vapour layer thickness

    Concetto Gianino 2008 Phys. Educ. 43 627

  10. Acceleration in one, two, and three dimensions in launched roller coasters

    Ann-Marie Pendrill 2008 Phys. Educ. 43 483

View by subject




Export








Please login to access our web services, or create an account if you don't yet have one.

You must have cookies enabled in your web browser to be able to login.

Username
Password

Forgotten your password? Get a new one here.