H-P Müller et al 1999 Phys. Med. Biol. 44 105 doi:10.1088/0031-9155/44/1/009
H-P Müller
, P Gödde
, K Czerski
, M Oeff
, R Agrawal
, P Endt§, W Kruse§, U Steinhoff§ and L Trahms§
The spatial distribution of high-frequency components in magnetic signals during the QRS complex of the human heartbeat was investigated. Cardiomagnetic signals were recorded simultaneously using 49 first-order magnetogradiometer channels of a multi-SQUID system with a low noise power density. The QRS fragmentation score S, as a measure of the fragmentation of the bandpass-filtered QRS complex, was examined for its sensitivity and specificity to discriminate 34 healthy volunteers, 42 post-myocardial infarction patients and 43 patients with coronary heart disease and with a history of malignant sustained ventricular tachycardia or ventricular fibrillation. The multichannel information was visualized by two-dimensional mapping of the score values of the single channels. By averaging the score values for the seven central channels,
, the score values of all 49 channels,
, and calculating the standard deviation for all 49 channels,
, a higher sensitivity and specificity for detecting patients with ventricular tachycardia (VT) or ventricular fibrillation (VF) was reached than by analysis of a single channel. Combination of these parameters furnishes a sensitivity of 90% and a specificity of 70% for identifying patients prone to VT/VF.
The results were compared with diagnostic information obtained from the QRS duration of the signal as well as with results obtained by modified QRS integral mapping.
85.25.Dq Superconducting quantum interference devices (SQUIDs)
87.50.C- Static and low-frequency electric and magnetic fields effects
Issue 1 (January 1999)
Received 27 January 1998, in final form 28 October 1998
H-P Müller et al 1999 Phys. Med. Biol. 44 105
M Boutillon 1998 Phys. Med. Biol. 43 2061
M Boutillon and A -M Perroche 1993 Phys. Med. Biol. 38 439
K R Shortt et al 1993 Phys. Med. Biol. 38 1937
S Tavernier et al 1992 Phys. Med. Biol. 37 635
C P Oates 1991 Phys. Med. Biol. 36 1433
M Boutillon and A M Perroche-Roux 1987 Phys. Med. Biol. 32 213
T R Overton and P R J Burch 1966 Phys. Med. Biol. 11 47
Concetto Gianino 2008 Phys. Educ. 43 627
Ann-Marie Pendrill 2008 Phys. Educ. 43 483