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Physics and the production of antibiotics: 2

Robert Fairbrother1, Wendy Riddle1 and Neil Fairbrother2

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In an article in the preceding issue we discussed the design and construction of fermenters in which antibiotics are cultured. For industrial purposes these fermenters can range in size up to 500 m3. They have to be sterilized, filled with sterile culture medium and the culture itself and supplied with oxygen continuously. In some cases they must be given additional feeds during the fermentation run. This article looks at some of the problems of supplying the culture medium and maintaining it at the optimum operating conditions.


PACS

87.85.Lf Tissue engineering

82.39.Rt Reactions in complex biological systems

Subjects

Biological physics

Chemical physics and physical chemistry

Dates

Issue 2 (March 2006)

Received 3 August 2005



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