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CCQM-K14: Calcium amount content in serum

L Van Nevel, Y Aregbe and P D P Taylor

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KEY COMPARISON

This key comparison 'Ca in Serum' is a follow-up to the pilot study P14. The aim of the study is to demonstrate and document the capability of national metrology institutes to measure the Ca amount content in a serum sample. The comparison was an activity of the Inorganic Analysis Working Group of CCQM and was piloted by the Institute for Reference Materials and Measurements (IRMM, Geel, Belgium).

The following laboratories participated in this key comparison (in alphabetical order):

  • CENAM (Mexico)
  • CSIR-NML (South Africa)
  • IAEA (International Organization)
  • IRMM (European Union)
  • KRISS (South Korea)
  • LGC (United Kingdom)
  • NIST (United States of America)
  • NMi -VSL (The Netherlands)
  • PTB (Germany)
The majority of participants applied isotope dilution mass spectrometry (IDMS) using thermal ionization MS (TIMS), sector field or quadrupole inductively coupled plasma MS (ICP-MS) as the analytical technique. IAEA reported a combined result of AAS and ICP-OES for the Ca amount content in the serum. The Key Comparison Reference Value (KCRV) was agreed upon during the IAWG meeting in October 2003 at EMPA/St-Gallen as the weighted mean of the reported participants' results. Accordingly the equivalence statements were calculated.

Main text. To reach the main text of this paper, click on Final Report.

The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the Mutual Recognition Arrangement (MRA).


Dates

Issue 1A ( 1 January 2004)



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