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Journal of Physics D: Applied Physics

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Journal of Physics D: Applied Physics Volume 42 Number 3 Create an alert RSS this journal

G C Kim et al 2009 J. Phys. D: Appl. Phys. 42 032005 doi:10.1088/0022-3727/42/3/032005

Air plasma coupled with antibody-conjugated nanoparticles: a new weapon against cancer

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G C Kim1, G J Kim2, S R Park1, S M Jeon3, H J Seo3, F Iza4 and J K Lee2

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Abstract References Cited By

FAST TRACK COMMUNICATION

Ambient air plasmas have been known to kill cancer cells. To enhance selectivity we have used antibody-conjugated nanoparticles. We achieved five times enhancement of melanoma cell death over the case of the plasma alone by using an air plasma with gold nanoparticles bound to anti-FAK antibodies. Our results show that this new interdisciplinary technique has enormous potential for use as a complement to conventional therapies.


PACS

87.85.Qr Nanotechnologies-design

87.53.-j Effects of ionizing radiation on biological systems

87.19.X- Diseases

Subjects

Biological physics

Medical physics

Dates

Issue 3 (7 February 2009)

Received 5 November 2008, in final form 3 December 2008

Published 31 December 2008



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