Q A Pankhurst et al 2009 J. Phys. D: Appl. Phys. 42 224001 doi:10.1088/0022-3727/42/22/224001
Q A Pankhurst1,2,5, N T K Thanh1,2, S K Jones3 and J Dobson4
Show affiliationsA progress report is presented on a selection of scientific, technological and commercial advances in the biomedical applications of magnetic nanoparticles since 2003. Particular attention is paid to (i) magnetic actuation for in vitro non-viral transfection and tissue engineering and in vivo drug delivery and gene therapy, (ii) recent clinical results for magnetic hyperthermia treatments of brain and prostate cancer via direct injection, and continuing efforts to develop new agents suitable for targeted hyperthermia following intravenous injection and (iii) developments in medical sensing technologies involving a new generation of magnetic resonance imaging contrast agents, and the invention of magnetic particle imaging as a new modality. Ongoing prospects are also discussed.
87.85.Qr Nanotechnologies-design
87.19.Pp Biothermics and thermal processes in biology
87.50.wp Therapeutic applications
Issue 22 (21 November 2009)
Received 5 June 2008
Published 6 November 2009
Q A Pankhurst et al 2009 J. Phys. D: Appl. Phys. 42 224001
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